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AlpHa Measurement Solutions |
pH in Pharmaceutical & Biotechnology

pH in Pharmaceutical & Biotechnology

pH measurement plays a crucial role in various aspects of pharmaceutical and biotech applications, ensuring the quality, safety, and efficacy of pharmaceutical products. The following examples of sub-applications where pH measurements are critical:
  • Characterizing or identifying the pH of a Reference Listed Drug or Reference Standard
  • Shaker bags used in R&D, lab and production (single-use or reusable)
  • Fermentation and bioreactor applications
  • Dissolution testing of drugs, pills, and other media
  • pH screening of blood, saliva, and other fluid samples
  • Intracellular pH in cell, enzyme, and tissue activities
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  • pH Range: 0 to 14 pH
  • Response Time: 10s
  • Low Ionic Strength Response Time: < 30s
  • Drift: ±0.05 pH (in 24 hours)
  • Accuracy: ±0.02 pH
  • Temperature Range: -5 to 135°C
  • HF Resistant Option
  • Low Sodium Error Optional Glass
  • Low Ionic Strength Optional Glass and Reference
  • Warranty: 12 Months
  • Form Factor
    • 12 mm
    • Cartridge (single use available)
    • Process Body
    • Custom Options Available
  • Housing Material Options
    • Ryton® (PPS)
    • ABS
    • Epoxy
    • Polycarbonate
    • Kynar ® (PVDF)
    • Polyethylene
    • PEEK (including medical grade)
    • PVC / CPVC
    • Teflon ™ (PTFE)
    • Ultem® (PEI)
    • Glass
    • Metal
      • Stainless Steel
      • Other Metals Available
  • Thermistor Options
    • PT100 (type A & B)
    • PT1000
    • 10 kohm
    • 30 kohm
    • 100 kohm
    • Any commercially available thermistors and custom options
    • Common temperature accuracy is ±0.3°C and can vary based on thermistor option chosen
  • Reference System
    • Ag / AgCl
    • Calomel (Hg2Cl2)
    • Differential
    • Custom Options Available
  • Reference Junction Options
    • Double Junction
    • Single Junction
    • Custom Options Available
  • Reference Junction Material / Design
    • Ceramic Pin / Annular / Disc
    • Fiber / Pellon
    • Porous Plastic (PTFE / HDPE / PP)
    • Sleeve Junction / Free Flow (liquid / liquid or ground glass Joint)
    • Open Aperture 
    • Solid State
    • Custom Options Available
  • Solution Ground
    • Integrated in Thermowell
    • Integrated in Body Housing
    • Stand-alone
    • Custom Options Available
  • Reference Electrolyte
    • Sealed
      • Soft Gel
      • Solid Gel
    • Refillable
      • Liquid
      • Soft Gel
    • Custom Options Available
  • Glass Sensor Shape
    • Bulb
    • Dome
    • Flat
    • Spear
    • Semi Micro
  • Integrated Insertions
    • 3/4" NPT
    • 1/2" NPT
    • 1" NPT
    • PG 13.5
    • Custom Options Available
  • Analog
    • Millivolts
    • 4 – 20 mA
    • 0 – 5 V
    • 0 – 10 V
    • Custom Options Available
    • Custom options available with preamp capabilities
  • Digital
    • RS-485 MODBUS RTU
    • Custom Options Available 
  • Connectors
    • Integrated Connectors (detachable or cableless)
      • S7
      • S8
      • Integrated BNC
      • Variopin
      • Custom Options Available
    • Connectors with Cables (including temperature)
      • BNC
      • DIN
      • MOLEX
      • Mil-spec
      • 2.5 mm / 3.5 mm phono
      • RCA
      • Spade Lugs
      • Tinned Leads
      • LEMO
      • Circular Connectors
      • Any commercially available connectors and custom options available