AlpHa Measurement Solutions |
pH in Pharmaceutical & Biotechnology
pH in Pharmaceutical & Biotechnology
pH measurement plays a crucial role in various aspects of pharmaceutical and biotech applications, ensuring the quality, safety, and efficacy of pharmaceutical products. The following examples of sub-applications where pH measurements are critical:
- Characterizing or identifying the pH of a Reference Listed Drug or Reference Standard
- Shaker bags used in R&D, lab and production (single-use or reusable)
- Fermentation and bioreactor applications
- Dissolution testing of drugs, pills, and other media
- pH screening of blood, saliva, and other fluid samples
- Intracellular pH in cell, enzyme, and tissue activities
- pH Range: 0 to 14 pH
- Response Time: 10s
- Low Ionic Strength Response Time: < 30s
- Drift: ±0.05 pH (in 24 hours)
- Accuracy: ±0.02 pH
- Temperature Range: -5 to 135°C
- HF Resistant Option
- Low Sodium Error Optional Glass
- Low Ionic Strength Optional Glass and Reference
- Warranty: 12 Months
- Form Factor
- 12 mm
- Cartridge (single use available)
- Process Body
- Custom Options Available
- Housing Material Options
- Ryton® (PPS)
- ABS
- Epoxy
- Polycarbonate
- Kynar ® (PVDF)
- Polyethylene
- PEEK (including medical grade)
- PVC / CPVC
- Teflon ™ (PTFE)
- Ultem® (PEI)
- Glass
- Metal
- Stainless Steel
- Other Metals Available
- Thermistor Options
- PT100 (type A & B)
- PT1000
- 10 kohm
- 30 kohm
- 100 kohm
- Any commercially available thermistors and custom options
- Common temperature accuracy is ±0.3°C and can vary based on thermistor option chosen
- Reference System
- Ag / AgCl
- Calomel (Hg2Cl2)
- Differential
- Custom Options Available
- Reference Junction Options
- Double Junction
- Single Junction
- Custom Options Available
- Reference Junction Material / Design
- Ceramic Pin / Annular / Disc
- Fiber / Pellon
- Porous Plastic (PTFE / HDPE / PP)
- Sleeve Junction / Free Flow (liquid / liquid or ground glass Joint)
- Open Aperture
- Solid State
- Custom Options Available
- Solution Ground
- Integrated in Thermowell
- Integrated in Body Housing
- Stand-alone
- Custom Options Available
- Reference Electrolyte
- Sealed
- Soft Gel
- Solid Gel
- Refillable
- Liquid
- Soft Gel
- Custom Options Available
- Sealed
- Glass Sensor Shape
- Bulb
- Dome
- Flat
- Spear
- Semi Micro
- Integrated Insertions
- 3/4" NPT
- 1/2" NPT
- 1" NPT
- PG 13.5
- Custom Options Available
- Analog
- Millivolts
- 4 – 20 mA
- 0 – 5 V
- 0 – 10 V
- Custom Options Available
- Custom options available with preamp capabilities
- Digital
- RS-485 MODBUS RTU
- Custom Options Available
- Connectors
- Integrated Connectors (detachable or cableless)
- S7
- S8
- Integrated BNC
- Variopin
- Custom Options Available
- Connectors with Cables (including temperature)
- BNC
- DIN
- MOLEX
- Mil-spec
- 2.5 mm / 3.5 mm phono
- RCA
- Spade Lugs
- Tinned Leads
- LEMO
- Circular Connectors
- Any commercially available connectors and custom options available
- Integrated Connectors (detachable or cableless)